Skip to content
• For research use only. Not for human or animal consumption. Read the content policy

Site Feedback

Is it safe or not to order the hgh?

Started by southGina 27 replies 8 people Last activity

BBA Support
#25
✅ Correct Explanation in Simple Terms Here is the actual science simplified: 1. GH does two things: Stimulates liver → systemic IGF-1 (blood) Stimulates tissues → local IGF-1 (muscle, fat, organs) 2. Blood IGF-1 does not reflect local IGF-1 You can have: High blood IGF-1 + low local response Low blood IGF-1 + strong local effects This explains why blood tests can look “bad” even if GH is active. 3. High GH doses give more effects even if blood IGF-1 stops rising Because GH has direct, [tracking removed] effects. 4. Low IGF-1 blood results on GH do not mean the GH is inactive Blood IGF-1 is influenced by: Genetics Liver sensitivity Binding proteins (IGFBP-3, ALS) Nutrition Sleep Stress Time of blood draw So two people taking identical legit GH can have very different IGF-1 numbers. 🎯 If you’re trying to assess GH activity for your customers Tell them this: The only reliable indicators GH is active are: Increased water retention (especially hands) Numbness or tingling (CTS symptoms) Better sleep Higher fasting glucose Increased appetite after 1–2 weeks Increased lipolysis (fat loss around waist) Pumps in gym + vascularity changes Blood glucose rises, insulin sensitivity drops These effects happen even if IGF-1 test is flat.
Link Reply
#27
Quoted :: asiacally the systemic igf-1 level doenst tell you much. For anabolism the autocrine igf-1 is relevant. Thats why you have such huge difference in anabolic responses with similar igf-1 levels. Thats also the reason why even though systemic igf-1 didnt continue to increase in studys with more than 6IU rHGH bodybuilders report more anabolic effect with higher dosage. In lower rHGH dosages systemic igf-1 has even a negative effect on autocrine igf-1 which seems to be overwritten at higher dosages and of course while rHGH increases systemic igf-1 which may surpress autocrine igf-1 it also increases autocrine igf-1 at the same time.
Link Reply

That was the end of the thread

You just read 28 posts from 8 people in Site Feedback, written between Nov 2025 and Feb 2026.

Reading stays open to everyone — nothing here is behind a login. An account adds one thing: the ability to answer.