Skip to content
For research use only. Not for human or animal consumption. Read the content policy

Site Feedback

What's your experience with methylphenidate (Medikinet/Ritalin/Concerta)

Started by Member 2277 8 replies 6 people Last activity

OP
#1
What's your experience with methylphenidate (Medikinet/Ritalin/Concerta) while on GLP-1 peptides like tirzepatide (Mounjaro/Zepbound), semaglutide (Ozempic/Wegovy) or retatrutide? I started 10 mg methylphenidate retard (extended release) about 5 days ago, and I barely feel any effect. it seems super delayed or weak. I suspect it's because of the delayed gastric emptying from the GLP-1 (I'm on tirzepatide right now). Does anyone else have this? Did switching to immediate release (IR) help, or do you just need a higher dose? Or is the combo just not great overall?
Link Reply

That was the end of the thread

You just read 9 posts from 6 people in Site Feedback, written between Jan 2026 and Feb 2026.

Reading stays open to everyone — nothing here is behind a login. An account adds one thing: the ability to answer.

More in Site Feedback