From my experience making emulsions, sometimes you need to keep the solution moving/mixing til it cools. I think with heat, compounds will naturally separate out into their relative weights in layers until they lose heat. Reducing concentration is probably a good call too, I would assume oil solubility has limits like aqueous solutions.
I know it's not an emulsion but the concept still stands that they have different densities so you have to force the molecules to stay "in contact" by mixing until cool. Might not be the trick but would probably give you a better outcome next trial
I remade it with lower concentration of CoQ10, this time the coq10 remained dissolved in the mct oil without turning into a blob but the MCT oil and DMSO separated
oh might be right thakns. this time when I heated it the MCT and DMSO mixed, but after it cooled separated. maybe I try heating it again and keep the magnetic mixer on until it's fully cooled down?
Yeah that sounds like a solid approach. I was even thinking once you get the DMSO and MCT solution made first and cooled and stable, you should just be able to stir in the coq10 and it'll dissolve over time. Just a compromise that might just be the sacrifice in time required to make it work