JO
Jonah
1,083 posts·first seen Nov 2025
OP
I also wouldnt recommend tirz with reta because you're oversaturating the GIP receptors and Reta was made with a specific glucagon/GIP ratio in mind
JO
Jonah
1,083 posts·first seen Nov 2025
If you need something to dose with Reta, then your options are go higher, dose sema, or does cagri
JO
Jonah
1,083 posts·first seen Nov 2025
You could also do tesofensine, phentermine, etc.
BO
Bobbyyyy
383 posts·first seen Nov 2025
You think tesofensine is sensible long term?
JO
Jonah
1,083 posts·first seen Nov 2025
HB
HBBS
68 posts·first seen Mar 2026
has the highest weight loss in the trials
HB
HBBS
68 posts·first seen Mar 2026
people can titrate up to 6mg and that’s enough for 99% of people
HB
HBBS
68 posts·first seen Mar 2026
if that don’t work for you you’re a outlier
JO
Jonah
1,083 posts·first seen Nov 2025
I'm not saying it doesn't work lol. I'm just providing an explanation on why certain people might respond differently.
JO
Jonah
1,083 posts·first seen Nov 2025
Like 1mg sema > 6mg reta for me personally when it comes to appetite suppression
BO
Bobbyyyy
383 posts·first seen Nov 2025
BO
Bobbyyyy
383 posts·first seen Nov 2025
I lost 20kg in 2 abd a half/ 3 months on Reta
BO
Bobbyyyy
383 posts·first seen Nov 2025
BO
Bobbyyyy
383 posts·first seen Nov 2025
BO
Bobbyyyy
383 posts·first seen Nov 2025
Abd it just don’t work like that
BO
Bobbyyyy
383 posts·first seen Nov 2025
BO
Bobbyyyy
383 posts·first seen Nov 2025
Technically u shouldn’t get tolerant
AS
Ashatca178
215 posts·first seen Feb 2026
Bobby going around every server asking the same questions lol
BO
Bobbyyyy
383 posts·first seen Nov 2025
I reckon your brains dopamine and shit finds homeostasis and you get used to your new level of dopamine
BO
Bobbyyyy
383 posts·first seen Nov 2025