It’s relatively safe when IGF-1 is monitored, which is mandatory for every person being treated medically.
The same cannot be said for people blindly injecting some random amount of IUs, which tend to be far higher doses, but especially over a long periods. With rHGH so cheap that the lowest IQ can afford to run it year round with no clue what their IGF is will lead to disaster for some.
The problems are slow to develop, like organ enlargement and bone deformities, often difficult to detect, and not necessarily easily linked to GH use, since few would be willing to admit it to their doctors. Then what’s the likelihood they’ll post about it on social media.
Just recently you finally have some bodybuilders attributing the transformation of their facial structure to running GH at high doses, instead of blaming a permanent 50% increase in nose width and ear size, changes in shoe size, and rings no longer fitting, to “aging”.
Yet even people prescribed the typical low clinical rHGH doses have occasionally fallen through the cracks and weren’t properly monitored, so their IGF-1 went too high, and after a few years ended up in very bad shape.
If you want to be safe, you need to check IGF-1 and adjust dose so you either stay in physiological range, or no more than 1 standard deviation above it. And that’s going to be different for everyone. 6iu might be ok for one person and 2iu might be too much for another. If you don’t, and end up with a lifetime of joint problems and an enlarged, inefficient heart, don’t cry about not knowing the risks. Becoming “GH Ugly” and needing bigger shoes are the least of the problems.