quadruple-agonist" weight-loss and diabetes drugs like NA-931 (sometimes called bioglutide). This class of oral or injectable peptides targets GLP-1, GIP, glucagon, and IGF-1 (Insulin-like Growth Factor 1) to significantly reduce body mass while preserving lean muscle mass.
While NA-931 is currently advancing through clinical trials, there are a few important details to know about the role of IGF-1 in these next-generation treatments:
Muscle Preservation: Traditional GLP-1 and GLP-1/GIP treatments often result in the loss of both fat and lean muscle mass. The addition of IGF-1 is designed to combat this muscle wasting by promoting cellular growth and lean mass retention.
Energy Expenditure: Because these are "multi-agonist" drugs, they combine the appetite suppression of GLP-1/GIP with the fat-burning (lipolysis) and metabolic-boosting properties of glucagon.
Safety & Administration: These emerging candidates are primarily being developed as once-daily oral pills, bypassing the need for frequent injections. Early trial data suggests they may also bypass some of the severe gastrointestinal side effects (such as nausea and vomiting) often associated with older GLP-1 medications
Yes. Also adding IGF-1 to your Reta is essentially the same thing. IgF1LR3 is only meant to be run for for 4-8 week cycles followed by 2-4 weeks off though
It doesn’t. You won’t observe hyperplasia with LR3; at best, you’ll notice crazy pumps. If you don’t believe me (and can’t source increlex), run as much LR3 as you’d like for 8 weeks and compare your results to 8 weeks on 10+ IU of GH.
Im currently running HGH 6iu before bed fasted and i dont plan on stopping. I ran LR3 for 6 weeks and it certainly helped.
I will Increase dosages here and there on bulks but I don’t plan on stopping. It takes to long to benefit from it lol. I need to get some bloods done ASAP though.