MR
MrRMP
39 posts·first seen Nov 2025
OP
Can anyone here explain the pros and cons of pinning CU over topical?
Not sure which route I want to go with on this and look for opinions and benefits of each method
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
Ghk-cu is 500 daltons which is too large to penetrate the skin deep enough to truly have a sufficient effect. It would have to be encapsulated, along with micro needling to be more beneficial as a topical.
Whereas injecting it, it’s being absorbed into your bloodstream and you’re getting more of the compound than you would if you were only doing topical treatments
JO
Jonah
1,083 posts·first seen Nov 2025
Shouldn't this apply to every topical
JO
Jonah
1,083 posts·first seen Nov 2025
Like, injection vs topical cause systemic
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
It all depends on how large the molecules are. Like people going crazy over this salmon sperm crap (PDRN). That sht is way over 500 daltons 😬
There are plenty of face serums that are small enough to penetrate the skin and have an actual benefit but a lot of this crap being marketed is… crap
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
It also helps if the retinal/peptide has been encapsulated
JO
Jonah
1,083 posts·first seen Nov 2025
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
Then it will be able to be absorbed better
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
JO
Jonah
1,083 posts·first seen Nov 2025
Skin mommy, will you help my skin?
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
JO
Jonah
1,083 posts·first seen Nov 2025
Oh, nothing. I have some congestion that I can clear up w/an oil cleanse or a BHA. Outside of that, no fine lines or wrinkled at all. Maybe a little hyperpigmentation here or there.
But I'm really interested in skin peps. I had a buddy who was 25 who took klow for 2 months and he looked 16 again LOL.
JO
Jonah
1,083 posts·first seen Nov 2025
Overall, I'm probably the most interested in developing maintaining collagen/elastin
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
Yeah I can’t suggest klow enough
JO
Jonah
1,083 posts·first seen Nov 2025
Dope :3 do you think it'd be worth getting any of the other topicals like snap-8 or AHK-cu?
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
You could get some tretinoin from an India pharmacy, start with 0.025% cream
JO
Jonah
1,083 posts·first seen Nov 2025
I was gonna start with some otc adapalene cause I don't know how I'd react
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
Snap 8 is like topical botox so it’s not something that would benefit you since you don’t have any wrinkles or anything. Ahk-cu is better for hair growth
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
PE
Peppermint Petty
1,215 posts·first seen Oct 2025
Make sure to apply a moisturizer after to lock it all in