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Can anyone here explain the pros and cons of pinning CU over topical?

Started by MrRMP 64 replies 21 people Last activity May 18, 2026

OP
Nov 16, 2025 #1
Can anyone here explain the pros and cons of pinning CU over topical? Not sure which route I want to go with on this and look for opinions and benefits of each method
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Nov 16, 2025 #2
Ghk-cu is 500 daltons which is too large to penetrate the skin deep enough to truly have a sufficient effect. It would have to be encapsulated, along with micro needling to be more beneficial as a topical. Whereas injecting it, it’s being absorbed into your bloodstream and you’re getting more of the compound than you would if you were only doing topical treatments
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Nov 16, 2025 #5
It all depends on how large the molecules are. Like people going crazy over this salmon sperm crap (PDRN). That sht is way over 500 daltons 😬 There are plenty of face serums that are small enough to penetrate the skin and have an actual benefit but a lot of this crap being marketed is… crap
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Nov 16, 2025 #6
It also helps if the retinal/peptide has been encapsulated
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Nov 16, 2025 #8
Then it will be able to be absorbed better
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Nov 16, 2025 #12
Oh, nothing. I have some congestion that I can clear up w/an oil cleanse or a BHA. Outside of that, no fine lines or wrinkled at all. Maybe a little hyperpigmentation here or there. But I'm really interested in skin peps. I had a buddy who was 25 who took klow for 2 months and he looked 16 again LOL.
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Nov 16, 2025 #13
Overall, I'm probably the most interested in developing maintaining collagen/elastin
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Nov 16, 2025 #15
Dope :3 do you think it'd be worth getting any of the other topicals like snap-8 or AHK-cu?
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Nov 16, 2025 #16
You could get some tretinoin from an India pharmacy, start with 0.025% cream
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Nov 16, 2025 #17
I was gonna start with some otc adapalene cause I don't know how I'd react
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Nov 16, 2025 #18
Snap 8 is like topical botox so it’s not something that would benefit you since you don’t have any wrinkles or anything. Ahk-cu is better for hair growth
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Nov 16, 2025 #20
Make sure to apply a moisturizer after to lock it all in
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