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Can anyone here explain the pros and cons of pinning CU over topical?

Started by MrRMP 64 replies 21 people Last activity May 18, 2026

Nov 16, 2025 #21
Yeah, I was going to do a heavy moisturizer and if that's too occlusive, then I was going to sandwich a lighter one
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Nov 16, 2025 #22
Do you know if any other OTC peptide product is worth? I was looking at TOs multi-peptide serum
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Nov 16, 2025 #23
Sandwiching is good if you’re not sure how your skin will tolerate it but if you find it’s not irritated or peeling I’d skip the first layer of moisturizer because you’ll just been creating a little barrier which would make it harder for the adapalene to be absorbed
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Nov 16, 2025 #24
For sure, sandwiching is my option if reg moisturizer doesn't work
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Nov 16, 2025 #25
I love TO, their peptide serum is good. La Roche-Posay has some good products too. Their moisturizer is amazing
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Nov 16, 2025 #26
Do you think there's any merit in injecting matrixyl peptides?
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Nov 16, 2025 #27
I don’t think those are meant to be injected or no?
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Nov 16, 2025 #28
I wasn't sure LOL. I think I found raws and some people do offer them
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Nov 16, 2025 #29
Applying it topically and micro needling would help with deeper penetration but yeah don’t inject that lol
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Nov 16, 2025 #32
Is there even a point to topical ghk-cu if it's too big and I have klow?
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Nov 16, 2025 #33
I mean if you wanna take the time to micro needle it could have some benefits. I’ve been using it topically but once I run out of the jar I have, I’m just going to stick to injecting. It’s hard to tell if it’s doing anything because i’ve been doing both 😂
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Nov 16, 2025 #34
But if you’re currently running klow, glow or just ghk.. I’d just keep doing that
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Nov 16, 2025 #39
I 2nd la Roche possay, only moisturiser that doesn’t make me break out
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